Subject(s)
Skin Neoplasms , Tattooing , Risk Factors , Sunlight , Radiation, Ionizing , Burns , Cicatrix , Carcinoma, Squamous Cell , Warts , Granuloma , MelanomaABSTRACT
Rhabdomyosarcoma of the larynx is a very unusual neoplasm and delays in diagnosis are common because the presenting symptoms are often mistaken for inflammatory or benign laryngeal disease, therefore a high index of suspicion is necessary to make diagnosis. We report a 13 years old girl with diagnosis of laryngeal Rhabdomyosarcoma. The optimum treatment of head and neck rhabdomyosarcoma has not been defined. Therapeutic modalities include an aggressive surgery without major morbidity. Radiotherapy and chemotherapy is also preferred for the treatment of rhabdomyosarcoma
Subject(s)
Humans , Female , Laryngeal Neoplasms , Rhabdomyosarcoma/surgery , Rhabdomyosarcoma/radiotherapyABSTRACT
Pretibial epidermolysisbullosa is a rare variant of hereditary epidermolysisbullosa characterized by the delayed onset of lesions and their localization. We present two cases, a 35-year-old woman and a 21-year-old man. They clinically had pruritus, nodular prurigo-like or lichenified lesions, violaceous scarring, milia, nail dystrophy and in one case albopapuloid lesions on the trunk. Physical signs of disease were first noticed between 3 and 9 years of age. Histologic examination showed a subepidermal blister with milia formation, and a mild mixed inflammatory infiltrate. These patients represent annusual, poorly recognized form of dystrophic epidermolysisbullosa with features that resemble a variety of acquired dermatoses